This research comes to us from very reputable group of Dr. Yiyi Weng at Zhejiang University of Technology. This paper shows how to turn any Tryptophan into strange tertiary azide heterocycle with about 87% efficiency. Could be useful if no other functionalization methods are available. I am not sure how reactive this azide will […]
Very unusual method of turning Tryptophan into click-reactive handle Read More »
Here comes new modification of the Alkyne. Is this the new click chemistry? Through a modified Kinugasa reaction, a novel method of amidation on terminal oligo alkyne conjugates by copper-promoted oxidation with nitrones has been developed. Unprotected bifunctional carboxylic acid–amine reagents can be transformed directly to the respective amide products under these edited Kinugasa reaction
Very Interesting Alkyne Reaction Read More »
Samantha M. SarrettSamantha M. SarrettDepartment of Chemistry, Hunter College, City University of New York, New York, New York 10065, United StatesPh.D. Program in Biochemistry, Graduate Center of the City University of New York, New York, New York 10016, United StatesDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, United StatesMore by
Lysine-Directed Site-Selective Bioconjugation for the Creation of Radioimmunoconjugates Read More »