Better site specificity for Photoaffinity Labeling

I usually do not like to write about photoaffinity labeling reagents because of their indiscriminate nature. But this publication from the lab of Dr. Christina Woo in Harward. They were able to develop Cyclobutane Diazirine tags that can label Carboxylic Acids on the protein with variety of functionalities with pretty respectable efficiency (5-25%)!  They used […]

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