Very unusual way to add Azide to Tyrosine
This method comes to us from Switzerland’s very own Ecole Polytechnique Fédérale de Lausanne, group of Dr. Waser. They decided to functionalize Tyrosine using Hypervalent Iodine compounds. To be precise, they used ethynylbenziodoxolones (EBX). It was pretty selective to Tyrosine, compared to other nucleophilic residues, and was slightly reactive towards cysteine. But, if there is […]
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